Abnormal synaptonemal complex in an oligochiasmatic man with spermatogenic arrest

Chronology of meiosis & synaptonemal complex abnormalities in normal & abnormal spermatogenesis.

BACKGROUND & OBJECTIVES The study was taken up to define criteria of normality for meiosis by assessing the frequency of meiotic prophase cell types, the frequency of pachytene substage in normal and abnormal spermatogenesis and to determine what synaptonemal complex. METHODS A quantitative and qualitative analysis of the first meiotic prophase was performed in 10 patients presenting with non...

An Asymptomatic Man With an Abnormal ECG.

A 76-year-old man presented for a routine health evaluation. He reported no symptoms and the cardiovascular physical examination was within normal limits. He takes amlodipine for hypertension. He was referred for a cardiology evaluation after the following ECG was performed. Please turn the page to read the diagnosis. Juan Carlos Brenes, MD Carlos Brenes-Pereira, MD Alfonso Tolentino, MD Cornel...

Submandibular Hemangioma with Cardiorespiratory Arrest in an Infant

Hemangiomas are defined as soft tissue lesions in the maxillofacial or oral region. Hemangiomas of salivary glands constitute 30% of the non-epithelial tumors in major salivary glands.  Benign tumors in salivary glands are located 85% in parotid gland and 13% in submandibular gland. We present a case of submandibular hemangioma in an infant patient that had some complications and a challenging ...

Man with weight loss, fever, cough, and an abnormal spleen .

Epigenetics of the Synaptonemal Complex

Meiosis is a process composed of two divisions of the germ line cells without an intervenient S phase, thus there is no duplication of DNA between the first and the second meiotic divisions. The first meiotic division begins with the pre-leptotene that is the stage where the DNA replicates and chromosomes prepare to enter the meiotic prophase I in most of the organisms with sexual reproduction ...